55 Answered Questions for the topic DNA

Dna

10/22/19

DNA Repair in relation to cancer

Function of DNA repair in cancerous cells
Dna

10/02/19

what does DNA look like?

is a it a long bunched up strand or is it shaped like a chromosome (x shaped)?
Dna

08/02/19

Chromosome and chromatid numbers during cell cycle phases?

A diploid cell in G1 has 6 chromosomes. How many chromosomes and how many chromatids are present in each of the following stages?Here is what I am guessing- G1: 6 chromosomes ; 6 chromatids - G2:... more
Dna

07/31/19

What is the purpose of ethanol in a DNA extraction experiment?

We were doing a lab experiment in biology class in which we extracted DNA from a banana-detergent solution mixture.(The detergent solution was made of 100ml of detergent, 90ml of water, and 5g of... more
Dna

07/29/19

Basic Amino Acid Residue Binding Mechanism to DNA?

I understand that many protein DNA binding domains bind to DNA via basic residues such as Arginine and Lysine. But what is the mechanism used to bind to DNA and where on the DNA would these... more
Dna

07/07/19

DNA is charged negative. Where is all the positive charge in my body?

DNA is charged negative because of its phosphate backbone. Since charges need to be balanced (so that there are no charges building up somewhere), what is the positive charge which neutralizes this... more
Dna

07/06/19

What is the purpose of ethanol in a DNA extraction experiment?

We were doing a lab experiment in biology class in which we extracted DNA from a banana-detergent solution mixture.(The detergent solution was made of 100ml of detergent, 90ml of water, and 5g of... more
Dna

07/01/19

Why does high pH result in the denaturation of DNA?

In the Southern blot method, for example, a solution of NaOH is used to denature the DNA in the sample. I find this counterintuitive since I expected that $\ ext{Na}^+$ cations would neutralize... more
Dna

06/26/19

What are the roles of guanidine-HCl and ethanol in binding of DNA to silica?

I'm trying to understand how exactly the binding to silica gel (in kits) step works and I cannot find any papers which provide an explanation of the physics or chemistry; especially on the way that... more
Dna

06/26/19

Do transcription factors bind to both strands of DNA?

Do transcription factors (or generally proteins) bind to only single strand of DNA or both strands? Since it can have non covalent bonds to both strands in theory. I would like to know the... more
Dna

06/26/19

Do changes in an organism's cell modify the genetic information it uses for reproduction?

What I'm actually interested about is whether a modification in one cell during the life of an **asexually** reproducing organism affects its genetic information? Which cell's genetic information... more
Dna

06/25/19

How can you identify if a person is homozygous for a certain allele?

I've been thinking about starting a small private research project. In this project I need to find out whether a person is homozygous for a certain allele. The reason for this is that I'm really... more
Dna

06/22/19

How can someone share 50% of their DNA with their parents yet all humans share 99.9%?

I have heard that humans share 99.9% of their DNA with other humans. I have also heard that a child shares 50% of their DNA with their parents. How do I resolve this apparent contradiction? It has... more
Dna

06/14/19

Is there a term for when a detrimental gene can be positively selected for because of linkage to a very fit gene?

Let's say that some piece of DNA would be subject to extreme negative selection if it were independently inherited, but it is very closely linked to an extraordinarily fit gene, and so the complex... more
Dna

06/14/19

What is the origin of "melting" in molecular genetics?

I'm reading some papers about prokaryotic transcription mechanisms, and I've come across a term I haven't heard before: *DNA melting* or *promoter melting*. After reading a bit, it's pretty clear... more
Dna

06/11/19

why is DNA antiparallel? Can it be parallel?

My biology textbook mentions that DNA is antiparallel and it got me wondering... Can DNA be parallel? What would happen if it was parallel? could DNA still replicate right?
Dna

06/08/19

Do changes in an organism's cell modify the genetic information it uses for reproduction?

What I'm actually interested about is whether a modification in one cell during the life of an **asexually** reproducing organism affects its genetic information? Which cell's genetic information... more
Dna

06/01/19

Are there any DNA base sequences that are fully conserved between the genomes of all humans?

That is, they don't differ throughout the entire population. I understand of course that we can't DNA sequence every human, so by "fully" I mean there's an incredibly small probability of there... more
Dna

06/01/19

Why is the DNA helix anti-parallel?

Why is it that DNA strands are running in anti-parallel fashion? Given the chemical base-pairing, they could have been parallel just as well.
Dna

05/30/19

Chromosome and chromatid numbers during cell cycle phases?

A diploid cell in G1 has 6 chromosomes. How many chromosomes and how many chromatids are present in each of the following stages?Here is what I am guessing- G1: 6 chromosomes ; 6 chromatids - G2:... more
Dna

05/21/19

What makes DNA sticky-ends sticky?

When restriction enzymes jaggedly cut double stranded DNA it results in so called sticky ends. What is the substance that makes the DNA sticky?
Dna

05/21/19

Does DNA react in all of the ways most other acids do?

As I understand it from my basic chemistry, there are some fundamental reactions that exist between any acid and other substances for example acid-base reactions that form a salt, and the existence... more
Dna

05/11/19

Why is thymine not incorporated into mRNA?

I am aware that in transcription uracil bonds to adenine and not thymine. But what is it that actually prevents thymine from bonding to adenine in transcription, that is not present in replication?
Dna

05/06/19

Does our DNA change during our lives?

As far as I know, DNA is the construction protocol of all organisms on Earth. Does it change when influenced by time and environment (physical laws)? As parents with schizophrenia are more likely... more
Dna

05/04/19

Is there any other function of DNA?

We all know that DNA acts as a genetic molecule. Does DNA have any other function in the cell other than being a genetic material and carrier of information?
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