Asked • 06/14/19

What is the origin of "melting" in molecular genetics?

I'm reading some papers about prokaryotic transcription mechanisms, and I've come across a term I haven't heard before: *DNA melting* or *promoter melting*. After reading a bit, it's pretty clear that they're referring to the separation of DNA from the double stranded form to single strands.Maybe it's just because chemistry isn't my thing, but when I think of *melting* I think of a solid gaining enough energy to become a liquid. How did the term *melting* come to apply to DNA in this way? Does the term *melting* have a more general definition in terms of thermal chemistry?

1 Expert Answer

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Katharyn C. answered • 06/16/19

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