Newest genetics Questions | Wyzant Ask An Expert

06/29/19

What is the difference between gene silencing in plants vs animals?

One way cells can control gene expression is by silencing specific genes. Gene silencing is a cellular mechanism that occurs in both plants and animals that results in the silencing of the specific... more

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Genetics Splicing Introns

06/28/19

What are limiting factors for intron length?

For predicting genes from a sequenced genome, you need to set a maximum intron length. How long can introns get in animals? Is there some limit?

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Genetics Translation

06/28/19

Why is an allele dominant or recessive?

Alleles refer to duplicate genes, where one allele can be dominant over the other. What makes an allele dominant or recessive, given that both code for a single protein?.

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Genetics Polyploidy Genomes

06/27/19

Why does polyploidy give an evolutionary advantage?

I would like to know what advantages polyploidy holds. I have come across a few examples during my research of polyploidy, for example human adults' hearts contain 27% diploid, 71% tetraploid and... more

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Genetics Evolution Chromosome Polyploidy

06/27/19

Why is polyploidy much more common in plants than in animals?

There are very few animals with polyploidy like salamanders. Why is it that polyploidy is so uncommon in animals? On the other hand there are numerous examples of polyploid plants. If ut something... more

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Genetics Dna Protein Binding Transcription Factor

06/26/19

Do transcription factors bind to both strands of DNA?

Do transcription factors (or generally proteins) bind to only single strand of DNA or both strands? Since it can have non covalent bonds to both strands in theory. I would like to know the... more

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Genetics Bacterial Genetics Gene Mutation

06/25/19

Describe the structure, function and effects of gene mutations on the lac operon.

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Genetics Dna Primer

06/25/19

How can you identify if a person is homozygous for a certain allele?

I've been thinking about starting a small private research project. In this project I need to find out whether a person is homozygous for a certain allele. The reason for this is that I'm really... more

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Genetics Chromosome

06/24/19

Which of the two chromosomes in a pair is expressed?

I have completely dummy question.I have 23 pairs of chromosomes in the cells 23 single coming from my mother and 23 single from my father. So how my cell choose which chromosome, mother's or... more

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Genetics

06/24/19

Why do we still have genetic disorders that show anticipation?

Anticipation whereby symptoms of genetic disorders occur earlier and with more severity as it is passed from one generation to the next.So wouldn't these inherited diseases over a few hundred... more

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Genetics Cloning

06/24/19

Why are female clones more often produced?

As a student of biology when ever I come by artificial cloning, I always find examples of females being cloned - Dolly the sheep, CopyCat, Daisy, etc. The only male I could see was Fibro mouse and... more

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Genetics Mutations Replication Bacteriology

06/24/19

Which bacteria have the highest mutation rate?

From my reading on *M. tuberculosis*, I know that this organism has a pretty high mutation rate due to uncorrected sloppy replication, which leads to a high rate of development of spontaneous... more

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Genetics Eyes Evolution

06/23/19

How can fruit flies and mice share the same gene that says to build an eye if they evolved separately?

I saw a documentary where they inserted the gene of a mouse that basically is the starting "build an eye" command into a fruit fly, and a fruit fly eye grew. My question is, if eyes of different... more

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Genetics Dna Population Genetics

06/22/19

How can someone share 50% of their DNA with their parents yet all humans share 99.9%?

I have heard that humans share 99.9% of their DNA with other humans. I have also heard that a child shares 50% of their DNA with their parents. How do I resolve this apparent contradiction? It has... more

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Genetics Brain Autoimmune

06/22/19

How does de-myelination occur in multiple sclerosis?

From what I understand, only the oligodendrocytes are affected in multiple sclerosis, and they are attacked by T cells which cross the blood-brain barrier. This leads me to two questions:1. How is... more

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Genetics Mutations Codon

06/21/19

Are STOP codons impacted by base insertion or deletion mutation?

I am learning about base insertion and deletion mutations. An example in my textbook is given below.GUU CCA CAU AUC.So if there is an insertion (of guanine):GUU **G**CC ACA UAU C_ _ (there will be... more

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Genetics Genomics Gene Annotation Eukaryotic Cells

06/20/19

Overlapping genetic information in eukaryotes?

In my research, I look at a lot of gene predictions / annotations. Frequently, I see loci where multiple gene models overlap. I haven't taken a systematic approach to analyzing these cases, but I... more

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Genetics Homework Database

06/20/19

Where should I start looking for an online gene library?

Is there an online library that includes all known genes in stored in their nucleotide form of all living organisms? I'm presuming that such a database doesn't exist. So to kick of my search, how... more

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Genetics Mutations

06/19/19

How do transgenic transformations cause off-target phenotypes?

I read that transgene insertions can cause off-target mutations that result in a phenotype being overly ascribed to the transgene, e.g. the increase of lifespan being ascribed to Sir2... more

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Genetics Terminology Synthetic Biology

06/18/19

Difference between genetic engineering and synthetic biology?

I've recently seen the term *synthetic biology* being used to describe research involving genetic modification of organisms. What is the difference between *synthetic biology* and *genetic... more

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Genetics Natural Selection Crispr

06/17/19

How could a species be engineered to go extinct?

Non-biology background here.I read this very interesting article: https://www.wired.com/story/crispr-eradicate-invasive-species/However I am having a hard time wrapping my head around... more

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Genetics Biology

06/17/19

We always say that enzymes are very specific to their substrates, then DNA polymerase can utilize all 4 types of nucleotides as substrates. to which substrate the DNA polymerase is specific?

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Genetics Mrna

06/17/19

Which patterns do I have to avoid when modifying the 3'-UTR?

I want to change a pre-miRNA sequence (in my case the pre-miRNA is encoding in a 3'UTR of a gene) and then put it in a lentivirus to see if it is still processed. After modification (permutation of... more

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Genetics Genomics

06/16/19

Which functional annotations could be useful?

Analyzing a genome, for a generic gene, which functional annotations (e.g from Gene Ontology) can help understanding its meaning/function or, at least, provide helpful informations? - Annotations... more

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Genetics Mitosis Cell Division

06/16/19

Why doesn't crossing over happen in mitosis?

If there was crossing over in mitosis, then there would various nature of somatic cells. May be that's the logic, but what is the mechanism? Why are there no crossover events during mitosis?

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What is the difference between gene silencing in plants vs animals?

What are limiting factors for intron length?

Why is an allele dominant or recessive?

Why does polyploidy give an evolutionary advantage?

Why is polyploidy much more common in plants than in animals?

Do transcription factors bind to both strands of DNA?

Describe the structure, function and effects of gene mutations on the lac operon.

How can you identify if a person is homozygous for a certain allele?

Which of the two chromosomes in a pair is expressed?

Why do we still have genetic disorders that show anticipation?

Why are female clones more often produced?

Which bacteria have the highest mutation rate?

How can fruit flies and mice share the same gene that says to build an eye if they evolved separately?

How can someone share 50% of their DNA with their parents yet all humans share 99.9%?

How does de-myelination occur in multiple sclerosis?

Are STOP codons impacted by base insertion or deletion mutation?

Overlapping genetic information in eukaryotes?

Where should I start looking for an online gene library?

How do transgenic transformations cause off-target phenotypes?

Difference between genetic engineering and synthetic biology?

How could a species be engineered to go extinct?

We always say that enzymes are very specific to their substrates, then DNA polymerase can utilize all 4 types of nucleotides as substrates. to which substrate the DNA polymerase is specific?

Which patterns do I have to avoid when modifying the 3'-UTR?

Which functional annotations could be useful?

Why doesn't crossing over happen in mitosis?

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