Are STOP codons impacted by base insertion or deletion mutation?

Question

I am learning about base insertion and deletion mutations. An example in my textbook is given below.GUU CCA CAU AUC.So if there is an insertion (of guanine):GUU **G**CC ACA UAU C_ _ (there will be a detrimental effect on the protein created).I'm a bit confused about how the stop codon will be read. If we have a new example with a stop codon:GUU CCA CAU AUC UAGWhen the mutation occurs (insertion of guanine) will it become:1) GUU **G**CC ACA UAU CUA GOR2) GUU **G**CC ACA UAU C_ _ UAGIf mutation 1) occurs, there would be no stop codon, but mutation 2) looks strange to me. So which is the right one?Thanks

Answer 1

In the region you were given, the result would be 1. What comes after C might include a stop codon. It probably would eventually. Your example is a little unrealistic, because insertions often create stop codons earlier than the original stop codon, because of the rearrangement of codons.