64 Answered Questions for the topic Neuroscience

05/11/19

Why do antidepressants have a delayed onset of action?
Why do antidepressants take so long to reach efficacy? I've read of theories about it perhaps being due to the strength of negative feedback via serotonergic and adrenergic autoreceptors during the... more
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05/10/19

Effects of exercise on the brain?
I am well aware of the phenomenon of neurogenesis induced by exercise, as well as the dopamine release that results from exercise. I am really interested in neuropsychology and the effects of... more
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Neuroscience Anatomy

05/05/19

Is the enteric nervous system found only in vertebrates?
The enteric nervous system is distinguished by being autonomous from the central nervous system and capable of independent action, such as the peristaltic reflex. For this reason the the intestines... more
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05/04/19

What physiological processes give rise to a linear cell survival curve?
If we plot the number of surviving cells in a structure over time (assuming no replacement), the shape of that curve should imply something about the underlying process responsible for cell death.... more
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Neuroscience Music Psychology Brain

05/03/19

Why do people like to listen to sad songs?
Why do people like to listen to sad songs? Sadness is not a positive feeling, so people should avoid it, right? Listening to sad songs is like inflicting some pain to yourself just for... more
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05/02/19

Why are there no Nissl bodies in the axon?
What could be the significance of not having Nissl bodies (endoplasmic reticulum) in the axon hillock (a part of the cyton) and axon? Does it have something to do with the processing of action... more
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04/26/19

Why do the brains of cocaine-users shrink faster than the brains of non-cocaine users?
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Neuroscience Pharmacology

04/19/19

If D1 receptors stimulate adenylate cyclase (through GPCRs) and D2 receptors inhibit it, then why do mutations in both have similar effects?
D1 and D2 both refer to specific types of dopamine receptors.I'm sure it has something to do with the fact that the D1 receptors are in regions different from D2 receptors.I know that adenylate... more
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04/16/19

What is the mechanism responsible for the periodicity of hiccups?
Hiccups ([*singultus*]) are caused by involuntary spasm of the intercostal muscles and diaphragm, producing a sudden inspiration with associated glottic closure. It seems the neurobiology of the... more
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04/16/19

Why does sympathetic activity constrict pulmonary vessels?
I don't know understand why sympathetic stimulation constricts pulmonary vessels? I thought that the sympathetic nervous system activated the body for physical activity. Physical activity would... more
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04/16/19

What's the mechanism for being mentally tired?
I notice that after long tests, or long periods of critical thinking, my body and mind feel noticeably tired. Why does this happen? Are the neurons in my head not firing as quickly, or is there... more
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04/11/19

Human perception of time depending on age?
From what I can tell and what thus far all people with whom I discussed this subject confirmed is that time appears to "accelerate" as we age.Digging a little, most explanations I found basically... more
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04/09/19

Is HSV-vector-mediated miRNA expression in dorsal root ganglia stable?
My question is on the following article: "*[Reduction of voltage gated sodium channel protein in DRG by vector mediated miRNA reduces pain in rats with painful diabetic... more
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04/05/19

Are thoughts transferred along with a brain during a brain transplantation?
If I'm transplanted with, e.g., Stephen Hawking's brain, would I start to think like him, or would I remain to think like me? On which, "thinking" ability depends , is it the physical structure of... more
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04/02/19

What actually happens when my leg 'falls asleep'?
Most people have experienced the temporary loss of feeling and tingling in their leg resulting from sitting in an abnormal position for a short while. Usually you get a loss of feeling in your leg... more
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04/02/19

Missing cells from immunopanning?
Why do I not have any cells left in my positive panning plate after transferring from the negative panning plate during immunopanning? I am trying to purify retinal ganglion cells from postnatal... more
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04/02/19

What are the neurobiological factors related to depression?
While it is agreed that neurotransmitters aren't the primary "cause" of depression, what other factors are a part of this mental illness that focus on the neurobiological aspects of it?
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03/27/19

How to make GABA pass the blood brain barrier?
I thought of methylating GABA at the gamma amino group in order to make it pass the blood brain barrier, but would it work?The goal is to make a sedative. Like GHB or benzodiazepines (I know that... more
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03/26/19

Can neurotransmitter depletion cause short-term drug tolerance?
**I'm curious to know if neurotransmitter degradation factors into drug tolerance and neural conduction and, if so, to what extent.** As I recall from textbooks I read as an undergrad, one... more
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Neuroscience Pharmacology Toxicology

03/26/19

Why is Botulinum toxin the most potent poison known?
Botulinum toxin (trade name Botox) inhibits acetylcholine release in neurons and causes botulism, an acute paralytic disease which leads to nerve degeneration and takes a long time to recover. I've... more
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03/19/19

Is there a disorder that causes one to feel heat from an inanimate object?
We just met a woman that feels heat (literally, hot enough for her to say she was burned) from inanimate objects. She says it is mainly the floors and chairs in her home, and she is unable to walk... more
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03/19/19

Why is Capsaicin injection not used instead of nerve surgeries for pain?
High concentration capsaicin kills c & a-delta nerve fibers permanently or at least long term. This has been known for 30 years. But capsaicin is only used in creams and patches, and not for... more
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03/18/19

What is the name of the bias that associate a thing as good because it has a relation to another good thing?
A customer buys X from "brand A" and has positive experience with it. "Brand A" also sells Y. Now the customer things it is good to buy Y because of his/her positive experience with buying X from... more
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Neuroscience Biology Human Biology

03/18/19

How do the brain and nerves create electrical pulses?
The information between the brain and peripheral nerves is sent via electrical pulses or signals, How then does a non-metallic human cell manage to conduct an electrical signal?
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03/17/19

How and where, in the human brain, are memories stored?
Background: I am a computer programmer who is fascinated by artificial intelligence and artificial neural networks, and I am becoming more curious about how biological neural networks work. Context... more
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