3 Answered Questions for the topic psychoneuropharmacology

Psychoneuropharmacology Pharmacology Neuroscience Neurotransmitter


Why do antidepressants have a delayed onset of action?

Why do antidepressants take so long to reach efficacy? I've read of theories about it perhaps being due to the strength of negative feedback via serotonergic and adrenergic autoreceptors during the... more
Psychoneuropharmacology Pharmacology Neuroscience Pharmacokinetics


How to make GABA pass the blood brain barrier?

I thought of methylating GABA at the gamma amino group in order to make it pass the blood brain barrier, but would it work?The goal is to make a sedative. Like GHB or benzodiazepines (I know that... more
Psychoneuropharmacology Pharmacology Neuroscience


Why is atropine a CNS stimulant, although it blocks the muscarinic receptors in the brain?

I know that atropine is a muscarinic antagonist, so why does atropine have excitatory actions on the brain while it is blocking muscarinic receptors?

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