402 Answered Questions for the topic pharmacology
03/19/19
Why is Capsaicin injection not used instead of nerve surgeries for pain?
High concentration capsaicin kills c & a-delta nerve fibers permanently or at least long term. This has been known for 30 years. But capsaicin is only used in creams and patches, and not for...
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Pharmacology Pharmacokinetics
03/18/19
How are drug metabolism and detection related?
If someone is taking treatment for a psychiatric disorder (e.g. diazepine), then would traces of the metabolized drug be detectable in their sweat or saliva?
03/18/19
What is the motivation behind fluorinated pharmaceuticals?
From what little research I've done, it appears that a significant portion of modern psychoactive drugs are fluorinated in one way or another (for example, Buproprion, Fluvoxamine, or any number of...
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Pharmacology Physiology
03/18/19
Do pharmacodynamics and pharmacokinetics of the drug in animals are the same as in human?
I'm trying to understand the purpose of different clinical trial phases, and the following question comes into my mind : Do pharmacodynamics and pharmacokinetics of the drug in animals are the same...
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03/18/19
How does laughing gas (N₂O) work?
Laughing gas (N2O), well, makes people laugh. How does just a gas make us do that, there has to be some hormones at work...So, I wanted to know how this works? What is the mechanism?
Pharmacology
03/18/19
What is pharmocokinetics of a drug?
Pharmacology Human Biology
03/18/19
How does laughing gas (N₂O) work?
Laughing gas, well, makes people laugh. How does just a gas make us do that, there has to be some hormones at work...So, I wanted to know how this works? What is the mechanism?
03/16/19
What Role Antagonists Play in the Study of Drugs?
I am pretty unfamiliar to pharmacology. I'm doing a research on drug abuse, particularly opioids' mechanism of action. I encountered several times evidences that come from studies using...
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03/16/19
Why is atropine a CNS stimulant, although it blocks the muscarinic receptors in the brain?
I know that atropine is a muscarinic antagonist, so why does atropine have excitatory actions on the brain while it is blocking muscarinic receptors?
Pharmacology
03/16/19
Umbrella term for agonist, antagonist, inverse antagonist, etc.?
For most receptors there exist different ligands that induce different responses. Depending on the response these different ligands can be classified into different groups such as agonists,...
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03/16/19
İrreversible dopamine antagonist vs. Dopamine agonist?
Can a dopamine agonist reverse the effects of an irreversible dopamine antagonist?
Pharmacology Medication
03/16/19
Why does the weight matter when consuming a certain amount of a specific drug?
My question is actually referred to hallucinogenic substances, in particular to mushrooms.I can understand why alcohol or other substances that relate to body mass (fat in some cases) affect people...
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03/16/19
Do drugs' levo isomers have a better interaction with the receptors in our body than dextro isomers?
Examples of *levo* drugs include levothyroxine, levocitrizine, and levodopa. Is there any specific reason why the receptors in our body exhibit this stereoisomerism and hold a high preference for...
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03/15/19
Relationship between toxicity of drugs and negative effects on brain?
Are psychoactive drugs with lower lethal doses more neurotoxic (more damaging to the brain)? For example, tetrahydrocannabinol (one of the active components of cannabis) has a much higher lethal...
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03/15/19
Enzyme Inhibition in relation to Aspirin?
I see that aspirin (in part) works by inhibiting cycloxygenase isoenzymes and that this inhibiting is irreversible. I've had a few classes mentioning this topic in passing, but never with depth.I...
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Pharmacology Neurophysiology
03/15/19
How do drugs enter synapses?
Many psychopharmaceutical drugs change synapse chemistry or directly agonize neuroreceptors in the brain. For example, cabergoline is a D2 agonist.How do these compounds enter the physical...
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Pharmacology Autonomic Nervous System
03/15/19
Why should we preceed neostigmine by atropine in tubocurarine toxicity?
Why should we precede neostigmine by atropine in tubocurarine toxicity ?I know that neostigmine act as anticholinesterase thus increasing the number of Ach molecules rendering them able to displace...
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Dose age calculations
Your doctor has ordered 0.9 g of medication for your patience. You have 500 MG on hand what is the correct dose of medication to be administered to your patient?
Does age calculations
Your physician has ordered 2000 units of a medication to be administered to your patient. You have 8000 units on hand. What is the correct dose that should be administered to your patient?
Pharmacology
03/14/19
Why is pharmacology important?
need to figure out the institute for safe medication practice publishes a list of __ medical abbreviations and symbols using only the letters E O R O R U S N E
fill in blank by unscrambling the words
Pharmacology Neuroscience
03/14/19
What is meant by drug tolerance?
What is meant by drug tolerance?This question is in my biology textbook for IGCSE and I have no idea what drug tolerance is. It would be very helpful if someone could clarify. Thank you.
03/14/19
What is the biological mechanism underlying caffeine intolerance? (CYP1A2 or other?)?
As far as I can tell, caffeine metabolism occurs primarily via the CYP1A2 enzyme. I am curious as to whether mutations in the CYP1A2 gene are associated with caffeine intolerance. Some site that...
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Pharmacology
03/14/19
Compatibility drugs info?
Let's suppose that I take a DrugA for ProblemA and then I got this ProblemB and started to take DrugB. Are there general rules I can look up to figure out whether I can take DrugA & DrugB...
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