Bailey C.

asked • 12/05/15

Help! Please! Biology final question and I can't find anywhere in the book or online.

is it a set list of steps? Is it a formula? I cannot find it anywhere and its on my biology final. What steps are followed to sequence the gene for sickle cell anemia? 
Thank you in advance!!

Andrew M.

I'm not certain this is what you are looking for but I found the below:
1. Compare ESTs from a sickle cell anemia patient to the human genome (using BLAST).
2. Identify the gene(s) aligning the ESTs and download their sequences (using Map Viewer).
3. Identify whether the ESTs contain any known nucleotide variations (single nucleotide polymorphisms) (using dbSNP).
4. Determine whether a mutant form of the gene is known to cause a phenotype (using OMIM).
The above is from:


1 Expert Answer


Beth R. answered • 03/07/16

2 (1)

Biology & Chemistry Degrees w/ Teaching & Tutoring Experience

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