Humans have 46 chromosomes in total, with half coming from their mother and half from their father. Because we have two sets of chromosomes, we are also referred to as being "diploid" organisms.
Not all organisms have the same number of chromosomes that we do. Fruit flies, for example, have four chromosomes, and some species of toads have 33! These special types of toads are also unique because they have three sets of chromosomes, making them triploid organisms.