92 Answered Questions for the topic molecular biology
03/26/19
Why do 60S & 40S ribosomal subunits make an 80S ribosome (not 100S)?
Why do 60S & 40S subunits make an 80S (not 100S) ribosome and, similarly, 50S & 30S make 70S? 60+40 is not equal to 80, nor is 50+30 equal to 70, so why are the subunits of the 80S and 70S...
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03/26/19
Photosynthesis: What Powers the Splitting of Water?
The splitting of water is an endergonic (non-spontaneous) reaction, and thus would require energy (chemical work to be done) in order to happen. In Photosystem II, an enzyme catalyzes this...
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03/19/19
What happens to the precursor protein's signal sequence after it is cleaved?
Where does this signal sequence "go" after it has been cleaved by signal peptidase and what is its next function?
03/19/19
Is there anyone discovered new drugs by actively create mutations in drug-producing organism?
Recently I was reading about drug discovery.As far as I know, there are currently 2 sources of creating new compounds by:- Screening from natural sources.- Synthesizing by add/remove/replace-ing...
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03/19/19
Why is Capsaicin injection not used instead of nerve surgeries for pain?
High concentration capsaicin kills c & a-delta nerve fibers permanently or at least long term. This has been known for 30 years. But capsaicin is only used in creams and patches, and not for...
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03/18/19
How does Cro protein expressed by lambda phage kill its host?
I read that the DNA segment of lambda phage integrated in host DNA could switch between lysogenic state where cI represses the expression of *Cro* and lytic state where *Cro* expression takes over...
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03/18/19
How, on a physical level, does ATP confer energy?
When ATP is used as the energy currency to make, say, reaction X + Y → Z happen, is what happens on a physical level down at the molecular scale that during the reaction---**ATP + H2O → ADP + Pi** ...
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03/18/19
What is the purpose of the outer mitochondrial membrane?
The purpose of mitochondria is to generate ATP, utilising a chemiosmotic gradient across the inner mitochondrial membrane. Protons are pumped out of the mitochondria into the intermembrane space,...
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03/17/19
How and where, in the human brain, are memories stored?
Background: I am a computer programmer who is fascinated by artificial intelligence and artificial neural networks, and I am becoming more curious about how biological neural networks work. Context...
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03/15/19
Knockout and knockdown of gene?
Out of curiosity, I got this question whether knocking out (deletion) of a gene on one side and knocking down (RNAi) of the same gene on the other side will affect the cell in a similar manner or...
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03/15/19
Enzyme Inhibition in relation to Aspirin?
I see that aspirin (in part) works by inhibiting cycloxygenase isoenzymes and that this inhibiting is irreversible. I've had a few classes mentioning this topic in passing, but never with depth.I...
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Why is DNA antiparallel? Can it be parallel?
My biology textbook mentions that DNA is antiparallel and it got me wondering... Can DNA be parallel? What would happen if it was parallel? could DNA still replicate right?
Molecular Biology Genetics
03/14/19
How are the boundaries of a gene determined?
What statistical processes and methods are used by geneticists/molecular biologists to know where one gene starts and one ends?
03/14/19
Redundancy of the genetic code?
One particular codon codes only for one amino acid, but an amino acid can be coded for by several different codons. Now according to the genetic code, the codon `UUU` codes for the amino acid...
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