
Eran W. answered 01/18/20
Nurse Practitioner with Extensive Pharmacology Tutoring Experience
1) A healthcare provider has ordered dobutamine 10 mcg/kg/min IV for your 68 YO patient who weighs 172 lb. The dobutamine is available as 1000 mg/250 mL. At what rate will you set the IV infusion pump?
Wojcik, Bradley J.. Nursing Dosage Calculation Workbook: 24 Categories Of Problems From Basic To Advanced! (Dosage Calculation Success Series) (p. 122). Nurse Superhero. Kindle Edition.
Eran W. answered 01/18/20
Nurse Practitioner with Extensive Pharmacology Tutoring Experience
Huong N. answered 07/03/20
Doctor of Pharmacy, PharmD degree, CA registered RPh
Abbas K. answered 01/19/20
PhD in Pharmacology with 7+ Years of Expert Teaching Experience
Hello student,
This is a very typical question for healthcare students and yet a very important one. It's simple and direct, however, it could turn out tricky if you miss the units.
The question asks to find the rate at which the IV pump should be set so that the patient receives the right amount of the dose, based on his body weight.
Step 1: Find the dose required by the patient:
Patient weight: 172 lbs. However the dose is given as 10 mcg/kg/min (which is in Kgs)
So convert lbs to Kgs: 172/2.2 = 78.18 Kgs (1 Kg = 2.2 lbs)
Since per Kg dose of the drug is 10 mcg/min. Therefore, the patient requires: 78.18 x 10 = 781.8 mcg/min.
Now, dobutamine is available as 1000 mg/250 mL (which is mgs and not mcg).
Therefore, we convert the mcg dose to mg: 781.8 mcg/min = 0.7818 mg/min (1 mg = 1000 mcg)
Now, most IVs are given for a period spanning in hours. Therefore, the patient dose is 0.7818 x 60 = 46.9 mgs/hour.
Since, dobutamine is available as 1000mg/250 mL. Therefore, we need to calculate the volume of this drug to be administered to the patient through 1 hour, to deliver 46.9 mgs.
Therefore, (46.9 x 250)/1000 = 11.7 mLs/hour
Hope this helps. Good luck!
Abbas
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