LEADING ROLE is a character/actor that is most of the feature film. The lead character(s) is the reason the other characters are needed. They lead the story. The lead is the "protagonist". The lead has the largest part in the project.
SUPPORTING ROLE is exactly that! Supporting the lead actor. The supporting role gives a connection from one scene to another or connection from one character to another. Supporting actors have more lines that a "day player"/bit part and usually have a meaningful connection with the LEAD ROLE.