Where, on the mRNA coding for such a protein, would the ER signal sequence likely be located?

Question

A. The signal sequence is not part of the mRNA and is added separately by an enzyme.

B.Immediately before the stop codon.

C. Anywhere in the mRNA.

D.Immediately after the start codon.

Answer 1

D. Is the best answer. Immediately after the start codon will be the N-terminus of your protein. Thus, the signal sequence will be found at the N-terminus of the protein, which will then be cleaved at the endoplasmic reticulum.