Alesha V.

asked • 02/08/21

Clinical Scenario Question about Osteoarthritis

A 65-year-old obese woman with a diagnosis of osteoarthritis (OA) has been having increased pain in her right knee that is made worse with movement and weight-bearing and is relieved by rest. Physical examination reveals an enlarged joint with a varus deformity; coarse crepitus is felt over the joint on passive movement.  

  1. Compare the pathogenesis and articular structures involved in OA with those of RA. 
  2. What is the origin of the enlargement of the affected joint, the varus deformity, and the crepitus that is felt on movement of the affected knee? 
  3. Explain the predilection for involvement of the knee in persons such as this woman. 


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