Which of the following about isoenzymes are true ?

Question

A.) They have the same primary sequence

B.) They localise in different tissues

C.) Isoenzymes have different isoelectric points

D.) They remain unaltered in health and diseases

I believe the answer is B and C am I correct?

Answer 1

Yes Elena, you are correct. Isoenzymes are just different forms of the same enzyme activity. However, they are seen in different proportions in varying tissues. They actually have different amino acid composition and sequence (hence making A false). Since they are seen in different tissues, B would be correct. Isoenzymes are actually identified in labs via electrophoresis, which would mean that C is also correct. Converse to choice D, isoenzymes are actually early indicators for diseases as they will be altered. Hope this helps!