The bonding of Acetylcholine to its muscarinic receptors on smooth muscle causes gated K+ channels to close. This action is described as what?

Question

Would it be inhibitory or excitatory and would the cell depolarize or hyper-polarize?

Answer 1

In some smooth muscle, there is a calcium-activated potassium channel which tends to repolarize the membrane after calcium influx. Activation of m-ACh receptors in these smooth muscle cells would suppress this K-conductance. How would you describe this? If the Ca-activated K-channel normally repolarizes the depolarized membrane, and activation of m-ACh-R suppresses this, then what is it called?

I'd be curious to see what answers you get, as this is somewhat ambiguous because of the neurophysiological definition(s) of excitatory, inhibitory, depolarization and hyper-polarization.