Jody P. answered 12/09/21
Experienced high school tutor specializing in AP Biology
Ribosomes are the site of protein synthesis within a cell. In eukaryotic cells, ribosomes may be found attached to the rough endoplasmic reticulum or free-floating in the cytosol. Proteins that are synthesized on ribosomes attached to the rough ER are destined to function at the plasma membrane or they may be destined for secretion from the cell. For example, a digestive enzyme such as salivary amylase would be assembled on an attached ribosome. It would move from the ribosome into the rough ER, then be transported through the endomembrane system of the cell until it gets packaged into a vesicle by the Golgi apparatus. Finally the vesicle would fuse with the plasma membrane and the enzyme would be secreted from the cell by exocytosis into order to function in the break down of starch inside a person's mouth. Proteins that are synthesized on free ribosomes remain within the cytosol to do their jobs. For example, glycolysis, which involves several enzymes for the catabolism of glucose, is a process that occurs within the cytoplasm of a cell. A glycolytic enzyme would be made on a free ribosome and then be released into the cytosol to participate in the glycolytic pathway.