Which of the answer(s) true ?

Question

Which of the following is characteristic of the DNA methylation process ? Select one or ones that apply.

A.) S-adenosyl methionine (SAM)

B.) Histone acetyl transferases (HATs)

C.) Histone deacetylases (HDACs)

D.) CpG dinucleotides

E.) DNA methyltransferases (DNMTs)

Answer 1

Should be A) SAM, D) CpG dinucleotides, and E) DNMTs

B and C are involved in histone acetylation, which modifies the Lys residues of the histone proteins and allows for greater access/expression of the DNA.

SAM is where the body gets the methyl group from (the CH3 attached to S in the methionine) to methylate DNA. The C in CpG sites are what get methylated to make 5-methyl-cytosines, which usually decreases expression of adjacent genes. DNMTs are the enzymes that transfer the methyl group from one to the other.