Can someone help me please?
A 45 year-old woman complaining of breast pain was diagnosed with having HER2-positive breast cancer. The patient underwent lumpectomy followed by a period of chemotherapy including adjuvant treatment. Over the course of their treatment, the patient developed a urinary tract infection that required antimicrobial therapy, which initially consisted of a trimethoprim/sulfametoxazole combination drug. However, the patient during the course of her therapy suffered multiple recurrent infections and was, consequently, enrolled in a clinical trial to test the efficacy of a new mannoside anti-infective agent.
Question: Discuss the roles of the three components of the patient’s treatment for her relapsing UPEC infection. Your discussion should include the pertinent virulence factors that contribute to the establishment of the infection and the initial treatment failure.