Can someone tell me how I should answer this question?

Question

A 45 year-old woman complaining of breast pain was diagnosed with having HER2-positive breast cancer. The patient underwent lumpectomy followed by a period of chemotherapy including adjuvant treatment. Over the course of their treatment, the patient developed a urinary tract infection that required antimicrobial therapy, which initially consisted of a trimethoprim/sulfametoxazole combination drug. However, the patient during the course of her therapy suffered multiple recurrent infections and was, consequently, enrolled in a clinical trial to test the efficacy of a new mannoside anti-infective agent.

Question: With reference to signalling pathways, discuss the pathogenesis of HER2-positive breast cancer. In your answer, include discussion on the differential diagnosis of this condition.

Answer 1

increase HER2 pathway due to mutation = activation of cellular pro proliferation, growth, and survival pathways that cause uncontrolled/unregulated cell growth = tumor. HER2 (+) breast caner makes up about 20-30% recorded cases and has a worse prognosis compared to Estrogen or progesterone (+) cancer's