How to calculate the dose on each basis for a patient weighing 150 lb and measuring 5 feet 8 inches in height?

Question

If the daily dose of a drug is given in the literature as 8 mg/kg of body weight or 350 mg/m2.

Answer 1

Dose based on weight:

8 mg/kg

150 lbs x 1 kg/2.2 lbs x 8 mg/kg = 545 mg dose

Dose based on m² (there are different equations for m² using different units of wt and height):

BSA(m²) = square root (height in inches x weight in lbs ÷ 3131) = sqrt (68 inch x 150 lbs/3131) = 1.80 m²

1.80 m² x 350 mg / m² = 632 mg dose