Can immune cells be recruited to an area of inflammation, and later go on to a second?

Question

With regards to innate or adaptive immune cells... can naive/immature cells such as neutrophils, monocytes, macrophage/dendritic cells or adaptive T-cells be recruited to an area of inflammation, for instance an infection in the gastric mucosa, then leave that area and be recruited to another different area of inflammation? Or once recruited to a site are they unresponsive to other events?

Answer 1

When studying inflammation and the immune response, yes there are “immune cells” they are mediated to travel to the area of acute inflammation. This concept, which in scientific terms is called chemotaxis and involves interleukin Number 7, and two other mediators- C5a And LTB4, who recruit the neutrophil cells to the area of inflammation or infection site.

On a further note, it should be learned that there are many subtypes of interleukins, and each has its own function. For example, another Interleukin in the immune system process of fever, includes IL-1 in addition to Tumor necrosis factor and Prostaglandin GE2.

Any further immune system or questions on how the inflammation and infection response mechanisms work in the body please don’t hesitate to email or message me! I love Immunology !

Sincerely,

Dr Farah