Where do amino acids get attached to tRNA and where is it synthesized?

Question

Some very basic parts of transcription/translation seem to be left out in various literature. I can't find the answer to this anywhere:How exactly is tRNA synthesized? I realize that mRNA is synthesized through transcription and I know a lot about that. However tRNA is supposedly synthesized the same way but every time you read about transcription they just talk about how the mRNA then gets this and that...?Where do the amino acids get attached? Is it in the nucleus or outside the nucleus?Thanks.

Answer 1

You are correct that tRNA (and rRNA) is also synthesized by transcription. Once the RNA has left the nucleus, it folds up into it's appropriate shape. There are specific proteins (enzymes) that interact with certain tRNAs in the cytoplasm to add the correct amino acid.

Answer 2

tRNA is synthesized by RNA polymerase III in the nucleus. Before it leaves, it goes through modifications.

One end of the tRNA is tasked with reading the mRNA. As the mRNA proceeds through this end, the opposite end of the tRNA is attaching amino acids. Once the mRNA is read, a corresponding amino acid is added to a growing poly-peptide chain. The growing poly peptide chain is located on the opposite end of the tRNA. I will attach a link in the comments that has pictures and further explanations of this process.