is a hydrophobic core considered secondary structure

Question

I was wondering whether the hydrophobic core is considered secondary structure? such as alpha helix and beta sheets

Answer 1

A hydrophobic core, like a hydrophilic core, is technically a characteristic of a secondary structure but is not a type of secondary structure itself. There are also examples, like amphipathic helices, that have the hydrophobic and hydrophilic residues partitioned on either side of the outer surface of the helix.

Answer 2

No. Well defined, repeatedly observed relationship among amino acids nearer in primary structural sense are secondary structures. Example alpha helix and beta pleatedsheets

Hydrophobic core is seen in tertiary structures

Answer 3

Hydrophilic core and hydrophobic core are considered part of the protein molecule itself. Secondary structures can be alpha helices and beta sheets which make up the tertiary structure. The core of the protein molecule is usually made up of hydrophobic amino acids with the hydrophobic R groups facing inwards. In a sense, I think hydrophobic core is the characteristic of the proteins final folded tertiary structure.

Answer 4

No, it is considered a tertiary structure instead! Tertiary structures are the 3-D structures comprising of the -R groups from the polypeptide. Hydrophobic interactions, in which nonpolar, hydrophobic -R, come together in the inside since that protects them from the "water" surrounding, left to the hydrophilic amino acids on the outside of the polypeptide.

Answer 5

hydrophobicity is just a measure of how soluble an amino acid is in water, respectively. In amino acids, hydrophobic molecules will be located on the interior portion of the protein, while hydrophilic will be more likely to be in contact with any aqueous solution.