Can a fungus become resistant to a chemical such as Potassium Permanganate?

Question

A friend used potassium permanganate solution to treat tinea on the hands/feet but after some initial success, the tinea seems to be making a comeback. Could the fungus develop resistance to potassium permanganate?

Answer 1

If this is seen typically numerous things could be happening. In general fungus infections of the feet (not athletes foot) but that of the toe nail are extremely hard not near impossible to treat and actually cure. so mostly the reason why the fungus "came back" was that either the potassium permanganate was old and had no effect, only killed the bacteria and some of the fungus but not all, the fungus was actually not affected by the form of treatment used, or the length of treatment was not enough aka duration was not long enough to see the affect of it actually clearing. One would have to culture out the fungus and then identified the species then run a sequence analysis to determine resistance gene present or not.