Macy M. answered 04/03/22
Science/Med Tutoring from Healthcare Worker
From an anatomical perspective, your diaphragm contracts downward when you inhale to expand the lungs. This larger volume creates larger airspace and the negative pressure sucks in air. If you are in an environment with negative pressure, you will not be able to breathe in and effectively intake any air, unless you found a way to make the negative pressure in your lungs even lower than the environment (breathing deeper). However, you would still be able to exhale. You would experience rapid shortness of breath and hypoxia, and as you would not be able to intake as much oxygen as necessary, still being able to exhale carbon dioxide, you would enter respiratory alkalosis.