From the following formula for a progesterone nasal spray, calculate the quantity of each ingredient needed to prepare twenty- four 15-mL containers of the spray.

Question

Progesterone 20 mg

Dimethyl-b-cyclodextrin 62 mg

Purif ed water, ad 1 mL

Answer 1

The ingredients are given to make 1 ml of spray. You want to make 24 15-ml containers. That's a total of 24 x 15 mll = 360 mls. So, you will need 360 times each ingredient.

Progesterone = 20 mg x 360 = 7200 mg = 7.2 g

DBC = 62 mg x 360 = 22,320 = 22 g

Progesterone: 20 mg / ml x 360 ml = 7200 mg = 7.2 g

DBC: 62 mg / ml x 360 ml = 22,320 mg = 22 g