How do I go about this? And what statistical test can I use?

Question

Hi,

I’m currently doing a science project on sickle cell disease, I’m researching to see how a well a few drugs can induce fetal haemoglobin in sickle cell disease patients.

Currently what I’ve done is gather results from clinical studies, in which I took the mean levels of fetal haemoglobin in all patients before the trial and the means of the level of fetal haemoglobin after the trial. I then put the numbers in a T test to calculate the efficiency of the drug to induce fetal haemoglobin. Is this correct?

If not how can I go about this? And what test can I use, id appreciate all your help. Thank you

Answer 1

T-test is a good start. For non-normally distributed independent samples you can use Mann-Whitney mean test or Wilcoxon median test.