Hi, Sami! Great question!
When the cells of our body produce CO2 as a waste product of metabolism, there are three ways that the CO2 can be transported back to the lungs to be expelled.
- Firstly, CO2 can undergo a reaction commonly referred to as the "bicarbonate buffer system". Through this reaction CO2 is effectively converted into bicarbonate ions (HCO3-). These bicarbonate ions, being more water soluble than CO2 are therefore more soluble in the blood. Once at the lungs, the bicarbonate ions are converted back into CO2 and exhaled.
- Secondly, CO2 can bind to blood transport proteins called hemoglobin. Although hemoglobin is commonly thought to be exclusively a "oxygen-transport protein", hemoglobin also contains non-oxygen binding sites that CO2 can bind to. These hemoglobin transport the CO2 molecules to the lungs where they are exhaled.
- Lastly, to a small extent, CO2 can be directly dissolved in the plasma of the blood itself. In other words, CO2 can diffuse into the blood from tissues where it travels through blood vessels to the lungs. Note that only a small portion of the total CO2 transported to the lungs uses this method.