Termination of eukaryotic transcription is best described as:

Question

genetics biology (Transcription and Translation)

**please explain answer

Termination of eukaryotic transcription is best described as:

Group of answer choices

The message is cleaved near a polyA signal and many adenines are added to the 3’ end

RNA Pol II encounters a hairpin and the polymerase falls off the DNA

Rho protein binds to the transcript inducing RNA Pol II to fall off the DNA

RNA Pol II falls off the DNA soon after the end of the gene and adenines are added to the 3’ end of the RNA

Answer 1

Using deduction we can narrow our options down. The second and the third options both describe different types of termination for prokaryotes, or in other words single cell organisms without a nucleus. So these are not applicable to this. So we are left to choose between 1 and 4. Here is where things get tricky, in eukaryotes there is no poly a signal to indicate where a poly a polymerase should function. Knowing this indicates that number 4 is the answer. It was made very tricky by both 1 and 4 discussing the poly A tail added at the end of rna. But 4 is the answer