What is the major difference between eukaryotic and prokaryotic cells?

Answer 1

The major difference between eukaryotic and prokaryotic cells is that eukaryotic cells have a nucleus and membrane-bound organelles (like mitochondria and the endoplasmic reticulum), while prokaryotic cells do not have a nucleus or these organelles. Eukaryotic cells are generally larger and more complex than prokaryotic cells, which are typically smaller and simpler.

Answer 2

The prefix "Eu" means "true", "pro" means "before", and "karyose" means "kernel" referring to the nucleus of a cell. Therefore, the major difference between eukaryototes and prokaryotes is the presence or absence of a nucleus.

Eukaryotes have a nucleus and prokaryotes do not.