
Lauren H. answered 03/08/19
Experienced High School Chemistry Teacher
From the Internet: The antitumor activity of vinblastine is thought to be due primarily to inhibition of mitosis at metaphase through its interaction with tubulin. Vinblastine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death
separate chromosomes during cell division.