
Jenny M. answered 06/12/18
Tutor
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PhD Candidate in Neuroscience with 3 Years Experience in Genetics
I've never seen an example of a SNP in a microsatellite. SNPs are often defined as a point mutation found in more than 1% of the population, which is highly unlikely if the SNP occurred in a microsatellite. When it looks like there might be multiple mutations, it is unlikely it would be classified as a SNP/microsatellite hybrid (for reference, it is widely agreed you can't have a SNP-STR hybrid, the presence of one excludes the possibility of the other). When there are multiple situations occurring at once, you have a complex variant, which you can try to break down into its component parts, but it will not contain both a SNP and microsatellite.