Explain the entire process of protein secretion, beginning with a mature mRNA leaving the nucleus, incorporating Blobel's signal hypothesis, and ending

Question

In 6-7 sentences, Explain the entire process of protein secretion, beginning with a mature mRNA(that encodes a secretory protein) leaving the nucleus, incorporating Blobel's signal hypothesis, and ending with the release of the protein from the cell

Answer 1

If you watch the video here

https://www.ibiology.org/ibioseminars/secretory-pathway-cells-package-traffic-proteins-export.html

starting at about minute 15, it goes through the process. 

The lecturer is Randy Schekman, who won the Nobel prize for work in yeast identifying genes encoding machines involved in the pathway. The work he's describing is by Gunther Blobel, who won the Nobel prize earlier for work in figuring out the process overall.

A shorter, more direct animation from Garland Science is here: https://www.youtube.com/watch?v=4qf1BSXn_tk