How many milliliters each of purified water and an isotonic sodium chloride solution should be used to prepare 30 mL of a 1% w/v isotonic solution of fentanyl citrate (E=0.11)?

Question

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Answer 1

1% W/V fetanyl citrate=

1g fentanyl citrate in 100 mL of water

In this example it they are using 30mL

1g (30mL/100mL)= 0.3 g

Volume of water needed for isotonic solution with E= 0.11

= (g of fentanyl citrate)( E value)/ (0.009)

= 3.66 mL of purified water

In an isotonic sodium chloride solution

Volume 0.9% NaCl needed=

30mL- 3.66mL= 26.34mL of isotonic sodium chloride solution