differences in Alkaptonuria

Question

Question: Comparison between the normal Gene and the gene that is affected by alkaptonuria? give a deep explanation

Answer 1

Hi Zan P.,

So knowing that there is a mutation that renders the enzyme homogentisic dioxygenase ineffective (either low activity, or no activity) isn't enough for you?

If you need the specific set of mutations that can do that, why don't you do an internet search for that enzyme and its mutations? It turns out to be prolifically subject to disruptive mutations -- the quoted article lists 157 of them, and states (in general terms) why they affect the enzyme's action.

You might end up with a link to: h t t p s:/ / w w w. sci enc edir ect. com / top ics / m edi cine - an d- dentistry / hom oge nti sa te - 1 - 2 - di oxy gen ase

you must manually remove all the spaces in the link reference before you follow it! Wyzant filters responses to remove direct links ....