What facts address the concern that Wolbachia-infected mosquitoes released into the environment will have a negative impact?

Question

What facts address the concern that Wolbachia-infected mosquitoes released into the environment will have a negative impact? 

(NOTE: Please change all question marks to checkmarks for correct answers or empty boxes for incorrect answers.)

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1. Wolbachia already occurs naturally in a significant number of insect species. Wolbachia already occurs naturally in a significant number of insect species.
2. Wolbachia kills any insect that it infects. Wolbachia kills any insect that it infects.
3. Wolbachia is not transmitted to animals. Wolbachia is not transmitted to animals.
4. Wolbachia is extremely rare in nature, so will hardly impact it. Wolbachia is extremely rare in nature, so will hardly impact it.
5. Volunteers who have been bitten by Wolbachia-infected bacteria do not become infected.

Answer 1

Wolbachia already occurs naturally in many insect species.

Wolbachia is not transmitted to animals.

Volunteers bitten by Wolbachia-infected mosquitoes do not become infected.

Wolbachia is one of the most widespread bacteria in nature, already present in ~40–60% of insect species. Releasing Wolbachia-infected mosquitoes is not introducing something new, but just adding it to species where it’s not naturally present.

Wolbachia only passes from mother to offspring in insects and arthropods. It does not infect humans, pets, or other vertebrates.

Studies confirm Wolbachia stays inside insect cells and does not get transmitted to humans or animals through bites.