
Rebecca G. answered 08/11/21
B.S. in Environmental Health with experience in Chemistry and Biology.
Every enzyme works for a specific substrate at certain conditions. If the conditions change, the enzyme can become deformed (denatured) and will no longer be able to bind to the substrate, therefore inhibiting their function. I am not sure how to fill out your table (what are you looking for specifically?) but for example:
- Pepsin is an enzyme that breaks up protein in the stomach's acidic environment. It work at an ideal pH of 2.5. If the stomach conditions become too basic (anything above approx pH4), the enzyme will no longer function.
- Most enzymes in the body work at around 37°C, if it gets too cold or too hot, enzymes will become denatured and can no longer bind to the substrate to perform their intended function.