How was glucose reabsorb during tubular reabsorption?

Answer 1

Glucose is absorbed in the proximal tubule by the SGLT2 Na+/Glucose co-transporter (80%-90%, the rest is absorbed by SGLT1 a little further along the proximal tubule). This transporter uses the Na+ gradient created by the Na+/k+ ATPase to move glucose against its concentration gradient. Thus, it is energy dependent (ATP). Up to approximately 200 mg/dL serum glucose, nearly 100% of the glucose in the glomerular filtrate is absorbed. Above this...glucosuria.