Which of these is an advantage of in-gel electrophoresis compared to gel-free approaches (choose one answer) ?

Question

A.) Allows the type of protein modification to be identified

B.) It is more sensitive

C.) Allows a greater range of proteins to be analyzed

D.) Intract proteins allow detection of changes in protein modofication

E.) Proteins are identified as part of the quantification

Answer 1

Just want to emphasize the point a little more here, gel electrophoresis is really good at telling you WHAT certain kinds of proteins are, which means it's easy to pick up whether or not a certain protein has been modified. But like I said in the video, it's less good once you need to get into the specifics of *how* things were modified, or the nature of those modifications. I hope this answer is helpful for you and if you have further questions feel free to ask.