When and how signal amplification can occur during signal transduction?

Answer 1

Signal amplification occurs after the neurotransmitter crosses the synaptic cleft. Summation is the sum of inhibitory post-synaptic potentials and excitatory post-synaptic potentials received after a neuron releases neurotransmitters following an action potential. Remember that a neurotransmitter can be either excitatory or inhibitory depending on the structure of the receptor that accepts the neurotransmitter. Therefore, signal amplification or inhibition depends wholly on the post-synaptic receptor.

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-DT