Would a cell that was missing the kinetochores on one of its chromosomes get past metaphase?

Question

1) No, because the spindle could not attach to that chromosome and pull it to the midline

2) No, because cohesion on that chromosome could not dissolve

3) No, because kinetochores are necessary for sister chromatids to be held together

4) Yes, because kinetochores do not have any affect on metaphase

Answer 1

The correct answer would be #1. Kinetochores are where the spindle fibers attach to during cell division to help move the chromosomes around the cell. If kinetochores are missing, then the fibers cannot attach and move it to the metaphase plate in the middle of the cell.