What function does the Wnt pathway play in Xenopus axis specification? How would you show that the Wnt pathway is both necessary and sufficient for this function?

Answer 1

Hi Dimitri,

This looks like a test question or similar, so I can't give you a direct answer. Being said, WNT signaling is one of the better studied signaling pathways in biology.

There are a number of publications you can look at, for example: PMC3579404

If you'd like help understanding these concepts, feel free to reach out - I have a doctorate in this field.