They are considered a revolutionary in clinical medicine due to their ability for immune modulation, having different modes of action such as cell killing, and/or neutralization of an infectious organism; through various processes in including blocking a physiologic ligand-receptor interaction or by recruiting immune cells and proteins (eg, phagocytes, natural killer [NK] cells, complement) that can kill the target cell.
For that reason, they are used to treat various disorders, including:
- Hematologic malignancies
- Solid tumors
- Immune disorders,
- Inflammatory bowel disease