What are Monoclonal Antibodies and why are they a revolutionary discovery in medicine?

Answer 1

They are considered a revolutionary in clinical medicine due to their ability for immune modulation, having different modes of action such as cell killing, and/or neutralization of an infectious organism; through various processes in including blocking a physiologic ligand-receptor interaction or by recruiting immune cells and proteins (eg, phagocytes, natural killer [NK] cells, complement) that can kill the target cell. 

For that reason, they are used to treat various disorders, including: 

1. Hematologic malignancies 
2. Solid tumors
3. Immune disorders, 
4. Hypercholesterolemia, 
5. Asthma,
6. Osteoporosis
7. Inflammatory bowel disease
8. Infections