
Gadi L. answered 08/13/19
Bachelors in Molecular Biology & Biochemistry. Research HIV genetics.
In mitosis, DNA is simply doubled and travels to either new cell. In meiosis, DNA is first doubled. Then tetrads are formed. A tetrad contains the duplicated and analogous DNA from both parents and its where crossover occurs. However, if parents don't have same number of chromosomes tetrads cant usually form because every chromosomes from one parent must find a chromosome from other parent. With no tetrad and recombination, everything else fails.
Here is useful picture comparing 2;: https://kaiserscience.files.wordpress.com/2015/01/meiosis_vs-_mitosis1315851705371.png