
Jesse E. answered 07/15/19
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It is a general rule that a larger size requires the physical aspects that only eukaryotic cells have. However, nature likes to break the rules. Case in point: Thiomargarita namibiensis. Discovered in 1999, this prokaryotic bacteria can be seen with the naked eye.

Jesse E.
https://web.archive.org/web/20100120043846/http://www.mpg.de/english/illustrationsDocumentation/documentation/pressReleases/1999/news17_99.htm07/15/19