Is there a difference in cytoplasmic pH between prokaryotes and eukaryotes?
The cytosolic pH in human cells is [around 7.4, but fluctuates as the cell is replicating](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2114443/). Prokaryotes and eukaryotes are vastly different in many ways. One thing they share is cytoplasm. Is there any general difference in the pH between these two cytosolic spaces? Any pointers to a previous investigation into this would be hugely appreciated. Ideally I'm after a quantified numerical comparison from a peer reviewed reference, but given the obscurity of the question that might be a tall order!Googling was to no avail. It's swamped with pH survival data.
Prokaryotes can have a vast range of pH values. "It depends" is a frustrating answer, but it's the honest one here. Bacteria are hugely diverse and can grow in a myriad of different conditions. Some grow in acid mine drainage (pH < 3). Others grow in soda lakes (pH > 9). You may find https://courses.lumenlearning.com/microbiology/chapter/the-effects-of-ph-on-microbial-growth/ a helpful explanation.
