J.R. S. answered 06/24/19
Ph.D. in Biochemistry with an emphasis in Neurochemistry/Neuropharm
Essentially, in a diphosphate compound, the two phosphate moieties are attached (bonded) to each other, as in ADP. In a bisphosphate compound, the two phosphate moieties are not attache to each other, but rather are bonded at different places in the compound.