Yes. Some of the most common combinations are には, では, にも, へも, への and からの, although there are many more.
Basically, most nouns need の to connect them to other nouns, and the additional particle provides additional information, such as movement. 君への手紙 = a letter to you; 君の手紙 = your letter (a letter written by you?); 君へ手紙 = a letter to you (but these nouns need to be connected with の).
And は makes the word before it into the topic of conversation, highlighting it in contrast to another thing. も, on the other hand includes.
This website provides a pretty simple rundown: https://www.wasabi-jpn.com/japanese-grammar/combined-particles/