Asked • 03/17/19

What is the purpose of requiring two separate binding systems for the antibody response?

I've read that in most cases, B-cell activation requires helper T-cells. This requires antigen binding by both antibodies and T-cell receptors, using two different antigen-binding proteins, recognizing two different epitopes.Why is this so complex? Would the overall antibody system still work if B-cells required only antibody/B-cell receptor binding?

2 Answers By Expert Tutors


Tobi S. answered • 06/20/19

5.0 (931)

Biosciences Mentor

Still looking for help? Get the right answer, fast.

Ask a question for free

Get a free answer to a quick problem.
Most questions answered within 4 hours.


Find an Online Tutor Now

Choose an expert and meet online. No packages or subscriptions, pay only for the time you need.